The U.S. Patent and Trademark Office published its Final Sequence Rule, June 1, 1998, entitled "Requirements for Patent Application Containing Nucleotide Sequence and/or Amino Acid Disclosures" (see Federal Register 63:104, 29620-29643, June 1, 1998). Furthermore, WIPO published its final version of WIPO Standard ST.25, November 1, 1998, entitled "Standard for the Presentation of Nucleotide and Amino Acid Sequence Listings in Patent Applications." The amended U.S. rules under 37 C.F.R. §§1.821-.825, as well as the corresponding foreign equivalents, were marshaled forward for the purpose of simplifying the sequence rules and creating an international, language neutral, standard for Sequence Listings.
These rules, which have effective dates of July 1, 1998, and January 1, 1999, respectively, still refer to applications containing DNA sequences that include at least ten nucleotides (four or more specifically defined nucleotides) and/or four or more specifically defined amino acids, which are filed after the respective effect dates.
In order to prepare a Sequence Listing correctly, we require a copy of the specification, claims, and figures (as much as possible in the original, editable format), as well as all cursory information (inventors, serial number, filing date, etc). While we can work from a hard copy only, a “non-OCR scanned” version of the data will reduce the time and cost associated with preparing the raw sequence and/or amendment data from scratch. Our technical staff will thoroughly review the “as filed” or “to be filed” disclosure, identify all relevant sequence data, and prepare all necessary documents to satisfy a valid submission.
Furthermore, "large" Sequence Listings are our specialty. In fact, we prepared several Sequence Listing submissions in 2010 that averaged 3.2 million sequences apiece. While such disclosures are unique, many patent applications contain several hundred or several thousand sequences, and thus, preparation of a valid Sequence Listing can be very time consuming, complicated and costly. We have the experience and expertise to handle these projects for you, easing the difficult task at hand, while offering the lowest possible cost to you and/or your client.